某医药公司产品组合优化(英文版)(ppt 24页)

某医药公司产品组合优化内容摘要：
Indications
Also known as disease
Each indication is considered as one business opportunity
e.g., AIDS
We use the terms “pipeline or project” to represent the NPD structure for a given indication
We use “approach” to represent a specific way (e.g., a compound, a biological molecule) of drug development tailored for a given indication.
Therapeutical Classes
Also known as therapeutical areas, groups, or categories
e.g., Anti-infective products
Each class has many different indications
We use the term “portfolio” to represent the NPD structure for many different indications, within or across different therapeutical classes. A portfolio has many different pipelines (or projects).
Portfolio construction is the sum of pipelines.
Process:
Develop a (not necessarily optimal) pipeline for each business opportunity independently and calculate the expected value
Rank order each business opportunity
Build a portfolio by supporting those business opportunities whose expected values are above a threshold (e.g., marginal return, IRR)
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